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Bonnard, B., Rouot, J. & Silva, C. J. (2024). Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome. Optimal Control Applications and Methods. 45 (2), 544-574
B. Bernard et al., "Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome", in Optimal Control Applications and Methods, vol. 45, no. 2, pp. 544-574, 2024
@article{bernard2024_1781580978701,
author = "Bonnard, B. and Rouot, J. and Silva, C. J. ",
title = "Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome",
journal = "Optimal Control Applications and Methods",
year = "2024",
volume = "45",
number = "2",
doi = "10.1002/oca.3089",
pages = "544-574",
url = "https://onlinelibrary.wiley.com/journal/10991514"
}
TY - JOUR TI - Geometric optimal control of the generalized Lotka–Volterra model of the intestinal microbiome T2 - Optimal Control Applications and Methods VL - 45 IS - 2 AU - Bonnard, B. AU - Rouot, J. AU - Silva, C. J. PY - 2024 SP - 544-574 SN - 0143-2087 DO - 10.1002/oca.3089 UR - https://onlinelibrary.wiley.com/journal/10991514 AB - We introduce the theoretical framework from geometric optimal control for a control system modeled by the generalized Lotka–Volterra equation, motivated by restoring the gut microbiota infected by Clostridium difficile combining antibiotic treatment and fecal injection. We consider both permanent control and sampled-data control related to the medical protocols. ER -
English