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Mesquita, A. R., Belsky, J., Li, Z., Baptista, J., Carvalho-Correia, E., Maciel, P....Soares, I. (2015). Institutionalization and indiscriminate social behavior: differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes. Physiology and Behavior. 152, 85-91

A. R. Mesquita et al.,  "Institutionalization and indiscriminate social behavior: differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes", in Physiology and Behavior, vol. 152, pp. 85-91, 2015

@article{mesquita2015_1732208819404,
	author = "Mesquita, A. R. and Belsky, J. and Li, Z. and Baptista, J. and Carvalho-Correia, E. and Maciel, P. and Soares, I.",
	title = "Institutionalization and indiscriminate social behavior: differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes",
	journal = "Physiology and Behavior",
	year = "2015",
	volume = "152",
	number = "",
	doi = "10.1016/j.physbeh.2015.09.015",
	pages = "85-91",
	url = "https://www.sciencedirect.com/science/article/pii/S0031938415301128?via%3Dihub"
}

TY  - JOUR
TI  - Institutionalization and indiscriminate social behavior: differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes
T2  - Physiology and Behavior
VL  - 152
AU  - Mesquita, A. R.
AU  - Belsky, J.
AU  - Li, Z.
AU  - Baptista, J.
AU  - Carvalho-Correia, E.
AU  - Maciel, P.
AU  - Soares, I.
PY  - 2015
SP  - 85-91
SN  - 0031-9384
DO  - 10.1016/j.physbeh.2015.09.015
UR  - https://www.sciencedirect.com/science/article/pii/S0031938415301128?via%3Dihub
AB  - Institutionalization adversely impacts children’s emotional functioning, proving related to attachment disorders, perhaps most notably that involving  indiscriminate behavior, the subject of this report. In seeking to extend work in this area, this research on gene X environment (GXE) interplay investigated whether the serotonin transporter (5-HTTLPR) and val66met Brain–Derived Neurotrophic Factor (BDNF) polymorphisms moderated the effect of institutional care on indiscriminate behavior in preschoolers. Eighty-five institutionalized and 135 home-reared Portuguese children were assessed using Disturbances of Attachment Interview (DAI). GXE results indicated that s/s homozygotes of the 5-HTTLPR gene displayed significantly higher levels of indiscriminate behavior than all other children if institutionalized, something not true of such children when family reared. These findings proved consistent with the diathesis-stress rather than differential-susceptibility model of person-X-environment interaction. BDNF proved unrelated to indiscriminate behavior. Results are discussed in relation to previous work on this subject of indiscriminate behavior, institutionalization and GXE interaction.
ER  -