Exportar Publicação

A publicação pode ser exportada nos seguintes formatos: referência da APA (American Psychological Association), referência do IEEE (Institute of Electrical and Electronics Engineers), BibTeX e RIS.

Exportar Referência (APA) 
Cosme, G., Arriaga, P., Rosa, P. J., Mehta, M. A. & Prata, D. (2023). Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study. Journal of Psychopharmacology. 37 (6), 566-576
Exportar Referência (IEEE) 
G. Cosme et al.,  "Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study", in Journal of Psychopharmacology, vol. 37, no. 6, pp. 566-576, 2023
Exportar BibTeX 
@article{cosme2023_1713449712981,
	author = "Cosme, G. and Arriaga, P. and Rosa, P. J. and Mehta, M. A. and Prata, D.",
	title = "Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study",
	journal = "Journal of Psychopharmacology",
	year = "2023",
	volume = "37",
	number = "6",
	doi = "10.1177/02698811231158233",
	pages = "566-576",
	url = "https://journals.sagepub.com/doi/10.1177/02698811231158233"
}
Exportar RIS 
TY  - JOUR
TI  - Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study
T2  - Journal of Psychopharmacology
VL  - 37
IS  - 6
AU  - Cosme, G.
AU  - Arriaga, P.
AU  - Rosa, P. J.
AU  - Mehta, M. A.
AU  - Prata, D.
PY  - 2023
SP  - 566-576
SN  - 0269-8811
DO  - 10.1177/02698811231158233
UR  - https://journals.sagepub.com/doi/10.1177/02698811231158233
AB  - Background: Human social behavior is modulated by oxytocin (OT). Intranasal administration of OT (IN-OT) is a noninvasive route shown to elicit changes in the autonomic nervous system (ANS) activity; however, IN-OT’s effect on the temporal profile of ANS activity at rest is yet to be described. Aims: We aimed to describe the temporal profile of IN-OT at six 10-min time windows from 15- to 100-min post-administration in 20 male participants at rest while continuously recording their pupillary in an eyes-open condition and cardiac activity in eyes-open and eyes-closed conditions. Methods: We used a double-blind, placebo-controlled, within-subjects design study where we extracted two proxies of parasympathetic nervous system (PNS) activity: high-frequency heart rate variability (HF-HRV) and pupillary unrest index (PUI); and a proxy of sympathetic nervous system activity: sample entropy of the pupillary unrest.
Results: In the eyes-open condition, we found an effect of IN-OT on the proxies of PNS activity: decreased PUI in the three-time windows post-administration spanning 65–100 min, and as an exploratory finding, an increased HF-HRV in the 80–85 min time window. Conclusions: We suggest there is a role of OT in PNS regulation that may be consistent with OT’s currently theorized role in the facilitation of alertness and approach behavior.
ER  -