Scientific journal paper Q2
Discovery of novel plant peptides as strong inhibitors of metalloproteinases
Dina Maria Carrilho (Carrilho, D. M.); Isabel Duarte de Almeida (Duarte de Almeida, I.C.); Rita Francisco (Francisco, R.); Cândido Pereira Pinto Ricardo (Ricardo, C. P. P.); Maria da Conceição Duque-Magalhães (Duque-Magalhães, M.C.);
Journal Title
Protein and Peptide Letters
Year (definitive publication)
2009
Language
English
Country
United Arab Emirates
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Abstract
Five novel metalloproteinase protein inhibitors (MPIs) with molecular mass between 5.6 and 8.9 kDa and acid/neutral pI were detected in lupin seeds and exhibited strong inhibitory activities against thermolysin and/or gelatinase B. These novel peptides constitute not only the first MPIs described in plants but also the first plant peptides with inhibitory activity against a matrixin.
Acknowledgements
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Keywords
Gelatinase B,Lupin quiescent seed,Matrixin peptide inhibitor,Metalloproteinase protein inhibitor (MPI),Thermolysin
Fields of Science and Technology Classification
  • Biological Sciences - Natural Sciences
Publication Identifiers
ci-pub-25305
WOS:000265799400013
cv-prod-id-823631
000265799400013
Other Publication Details
2009
Bentham Science Publishers
Web of Science©;
0929-8665 (print)
1875-5305 (online)
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1.080
16 5
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543 - 551
Yes
Printed