The aim of this study is to characterize, quantitatively and qualitatively, the global scientific outputs of Alzheimer´s Disease (AD), identify the trends of investigation and supply the researchers with new tools. The 9,753 articles obtained from the science citation index expanded database (SCI-E), from Web-of-Science, were analysed. A bibliometric methodology identifies the publications, citations, journals, authors, countries, institutions, keywords, areas of research and trends, during 1997-2017. There was an increasing trend of AD publications over time. The journals of "Neurobiology of Aging" and "Dementia and Geriatric Cognitive Disorders" have the largest number of publications and citations. The most productive country and institutions which published articles in this field are in the USA. Emerging countries in the last four years in AD research are People's Republic of China, Russia, Portugal, Taiwan, Chile, Iran, Colombia, and Argentina. Velas B is the author of more publications, while Cummings JL is the author more cited. A keywords analysis revealed that dementia, mild cognitive impairment, aging, diagnosis, risk, brain, amyloid precursor protein, depression, and memory are research hotspots of the AD. The focus before 2006 was on anatomy, histochemistry, biochemistry, physiology and some therapeutics. Between 2007 and 2011 the focus was directed at psychology, psychiatry, genetics, risk factors, and therapeutics. After 2011 it was born a different focus of research directed to applications of technologies to heath, molecular engineering, neuropsychology and applied phycology, maintaining some researching fundamental disciplines of medicine. Besides, it has appeared clinical guidelines and a new field of interest in the meta-analysis

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