PIONEER is an Alliance of European Universities dedicated to SDG 11 'Sustainable Cities and Communities', addressing the need for cities to become inclusive, safe, resilient and sustainable. The alliance brings together 10 impact-driven universities, including an associated Swiss partner, and covers 32 cities and 16 regions across Europe. By bringing together academics, public institutions, private organisations and citizens in our orchestration framework, we will develop joint challenge-based education, impact-driven research and innovation co-creation initiatives that contribute to many European, regional and urban agendas, such as the EU Green Deal and the 'Fit for 55' package. To this end, PIONEER will also be a facilitator of inter-institutional learning and a tool for institutional change. We will achieve this ambition through strategic integration at the institutional level: gradually aligning our individual strategies and institutional trajectories, building a common development strategy to become truly international institutions integrated in a federal framework.This framework will be inspired by the European Union, with a strong strategic centre that draws on and supports the diversity and autonomy of our partners to build a flexible and complementary academic ecosystem, while working together on a common strategy and development path. Committed to spreading European values and promoting inclusion and diversity, the PIONEER Open Campus will offer seamless mobility for students and unique leadership development opportunities for staff. Our Knowledge Hub will enable member universities and over 40 associated partners from regional ecosystems to work together on matters concerning SDG11.