Scientific journal paper Q1
Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: a longitudinal analysis
Carla Moleiro (Moleiro, C.); Sofia Madureira (Madureira, S.); Ana Verdelho (Verdelho, A.); Jose M. Ferro (Ferro, J. M.); Anna Poggesi (Poggesi, A.); Hugues Chabriat (Chabriat, H.); Timo Erkinjuntti (Erkinjuntti, T.); Franz Fazekas (Fazekas, F.); Michael Hennerici (Hennerici, M.); John O'Brien (O'Brien, J.); Leonardo Pantoni (Pantoni, L.); Emilia Salvadori (Salvadori, E.); Philip Scheltens (Scheltens, P.); Marieke Visser (Visser, M.); Lars-Olof Wahlund (Wahlund, L.-O.); Gunhild Waldemar (Waldemar, G.); Anders Wallin (Wallin, A.); Domenico Inzitari (Inzitari, D.); et al.
Journal Title
Journal of Clinical and Experimental Neuropsychology
Year (definitive publication)
2013
Language
English
Country
United States of America
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Abstract
Age-related white matter changes have been associated with cognitive functioning, even though their role is not fully understood. This work aimed to test a 3-factor model of the neuropsychological assessment battery and evaluate how the model fit the data longitudinally. Confirmatory factor analysis (CFA) was used to investigate the dimensions of a structured set of neuropsychological tests administered to a multicenter, international sample of independent older adults (LADIS study). Six hundred and thirty-eight older adults completed baseline neuropsychological, clinical, functional and motor assessments, which were repeated each year for a 3-year follow-up. CFA provided support for a 3-factor model. These factors involve the dimensions of executive functions, memory functions, and speed and motor control abilities. Performance decreased in most neuropsychological measures. Results showed that executive functioning, memory and speed of motor abilities are valid latent variables of neuropsychological performance among older adults, and that this structure is relatively consistent longitudinally, even though performance decreases with time.
Acknowledgements
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Keywords
Neuropsychological assessment,Confirmatory factor analysis,Longitudinal study,White matter changes,Aging
  • Basic Medicine - Medical and Health Sciences
  • Clinical Medicine - Medical and Health Sciences
  • Psychology - Social Sciences
Funding Records
Funding Reference Funding Entity
QLRT-2000-00446 Comissão Europeia
PEst-OE/SADG/UI4038/2011 Fundação para a Ciência e a Tecnologia

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