Artigo em revista científica Q1
Couples' willingness to donate embryos for research: a longitudinal study
Ana Catarina Samorinha (Samorinha, C.); Milton Severo (Severo, M.); Helena Cristina Ferreira Machado (Machado, H.); Bárbara Figueiredo (Figueiredo, B.); Claudia de Freitas (Freitas, C.); Susana Manuela Ribeiro Dias da Silva (Silva, S.);
Título Revista
Acta Obstetricia et Gynecologica Scandinavica
Ano
2016
Língua
Inglês
País
Reino Unido
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(Última verificação: 2019-11-15 13:32)

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Abstract/Resumo
Introduction: Decision-making on embryo disposition is a source of distress and is subject to change over time. This paper analyses the willingness of couples undergoing in vitro fertilization to donate cryopreserved embryos for research from 15 days after embryo transfer to 12 months later, taking into account the influence of psychosocial, demographic, and reproductive factors. Materials and methods: Prospective longitudinal study, with 74 heterosexual couples undergoing in vitro fertilization in a public fertility centre in Portugal, recruited between 2011 and 2012. Participants were evaluated twice: 15 days after embryo transfer and 12 months later. Results: A significant decrease in patients' willingness to donate embryos for research over time was observed [86.5% to 73.6%; relative risk (RR) = 0.85; 95% CI 0.76-0.95]. A higher education level (>12 years) [adjusted RR (RRadj) = 0.79; 95% CI 0.64-0.96], considering research on human embryos to be important (vs. very important) (RRadj = 0.59; 95% CI 0.39-0.85) and practicing a religion less than once a month (vs. at least once a month) (RRadj = 0.73; 95% CI 0.53-1.00) seemed associated with unwillingness to donate embryos for research over time. Change towards non-donation happened mainly among couples who first considered that it was better to donate than wasting the embryos. Change towards donation occurred mostly among those stating that their priority at time 1 was to have a baby and who became pregnant in the meantime. Conclusions: Quality of care guided by patients' characteristics, values, preferences, and needs calls for considering the factors and reasons underlying couples' willingness to donate embryos for research over time as a topic in psychosocial guidelines for infertility and medically assisted reproductive care
Agradecimentos/Acknowledgements
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Palavras-chave
Cryopreserved embryos,Decision making,Embryo disposition,In vitro fertilization,Longitudinal study,Patient-centred care
  • Medicina Clínica - Ciências Médicas
Registos de financiamentos
Referência de financiamento Entidade Financiadora
PTDC/CS-ECS/110220/2009 Fundação para a Ciência e a Tecnologia
IF/00829/2013 Fundação para a Ciência e a Tecnologia
SFRH/BD/75807/2011 Fundação para a Ciência e a Tecnologia
SFRH/BPD/80530/2011 Fundação para a Ciência e a Tecnologia
UID/SOC/03126/2013 Fundação para a Ciência e a Tecnologia
IF/00956/2013 Fundação para a Ciência e a Tecnologia
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