Chronic kidney disease is a rising health issue that affects millions of people worldwide. Early detection and characterization of this disease is essential for effective management and control. This disease is associated with several serious health risks, such as cardiovascular disease, increased risk of stroke, and end-stage renal disease, which can be effectively prevented by early detection and treatment. Medical scientists rely on machine learning algorithms to diagnose the disease accurately at its outset. Recently, adding value to healthcare is being accomplished through the integration of machine learning algorithms into mobile health solution. Considering this, this paper proposes a predictive model of three machine learning classifiers, including Support Vector Machine, Decision Tree, and Multilayer Perceptron for chronic kidney disease prediction. The performance of the model was assessed using confusion matrix and executed in popular machine learning software tools such as WEKA and Rapid Minor. The study found that support vector machine yielded the highest accuracy rate of 98% in predicting chronic kidney disease in WEKA among other standard classifiers by using 10-fold cross validation. In addition, the proposed prediction model has been compared with existing models in terms of accuracy, sensitivity, and specificity. The experimental results indicate that the proposed predictive model shows promising results. These findings could integrate with the development of mobile health solution and other innovative approaches to prevent and treat this debilitating condition.

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