Lista de Projetos

Despite decades of devoted research, cancer remains a tremendous health threat and societal burden. Europe's Beating Cancer Plan aims to improve the lives of more than 3 million people by 2030 by improving prevention, early detection, diagnostics, therapeutics, and quality of life. The biggest single hurdle here is the highly inadequate way cancer data, both from research and healthcare, are still being dealt with. While other areas of society (e.g. e-finance, e-commerce, logistics, travel, meteorology, etc.) have fully exploited advances in data and information technology to serve organisations as well as individual consumers, so far this has failed in the health domain. Consequently, cancer data are hard to Find, Access, make Interoperable and Reuse. Evidently this is not caused by lack of suitable technology, but rather by organisational, social and cultural causes. Inherently, solving the problem requires a cultural shift from the current craftsmanship approach to cancer research and data, to a drastic collaboration model at industrial scale. CANDLE therefore aims to scale-up and improve existing (inter)national health data infrastructures, align maximally with national EHDS implementations in member states, including HDAB’s, DAAMS’s and SPE’s. CANDLE will also identify and resolve potential barriers (https://www.health-ri.nl/en/participation/obstacles-removal-trajectory ) that jeopardize effective implementation of UNCAN.eu and ECPDC digital platforms. CANDLE aims to equipe data users and NCDN developers with a ‘ready-to-use' CANDLE Resource Kit in a process oriented (research journey, patient journey, data life cycle) way. In summary, CANDLE will provide an avenue towards a successful and highly desired data transformation in European cancer research and serve as a catalyzer for the UNCAN.eu and ECPDC platforms by advancing the development of NCDNs to reach the goal of the Cancer Mission and Europe’s Beating Cancer Plan, i.e. reducing the burden of cancer.

Este estudo dá continuidade à monitorização psicossocial das zonas de influência da central de incineração LIPOR II, iniciada em 1998, apresentando os resultados relativos ao ano de 2025 sobre o posicionamento da população residente face à central. A monitorização recorreu a um questionário estruturado reduzido, utilizado desde 2008, que nesta edição foi aplicado em formato online. O principal objetivo do estudo foi caracterizar as atitudes e perceções dos residentes relativamente à LIPOR II e avaliar se a experiência de viver nas proximidades da central influencia a sua qualidade de vida. Com base num modelo teórico de monitorização psicossocial, analisou-se o impacto da qualidade ambiental percebida e da ameaça percebida associada à central no bem-estar dos residentes, controlando variáveis sociodemográficas. Adicionalmente, o estudo considerou o papel moderador da distância da residência à central e do grau de ligação à comunidade, partindo do pressuposto de que uma maior proximidade e uma ligação mais forte ao local intensificam essas relações. Para tal, foram analisados indicadores de atitudes face à central, perceção de ameaça, qualidade ambiental percebida, bem-estar dos residentes e ligação à comunidade.  

Musical rhythm processing has been increasingly associated with children’s reading and writing skills. However, most existing studies rely on cross-sectional designs, focus on pre-reading stages, and leave critical questions unanswered. It remains unclear how the rhythm–reading/writing link develops over time, which mechanisms sustain it, and whether rhythm-based training can causally enhance reading and writing acquisition. This project will address these gaps through a randomized controlled trial that combines behavioral and neuroimaging methods. Portuguese children aged 6–8 will be recruited from public school and randomly assigned to rhythm-based music training, Orff-based comprehensive training (active control), or no systematic training (passive control). Training will last ~9 months—one school year—and will be delivered in the regular school context. Children will undergo pre- and post-training assessments of rhythm, reading, writing and fine motor skills, alongside measures of cognition, motivation, and sociodemographics. Structural and functional MRI will examine the neural substrates of rhythm–reading/writing relationships. We hypothesize that rhythm predisposition predicts reading and writing outcomes, mediated by phonological processes (for basic reading and writing skills) and motor processes (for writing fluency), and that rhythm training will produce specific improvements in rhythm perception and synchronization, leading to gains in reading (and writing-related skills), and enhance motor skills, and writing fluency as a result. Orff-based training is expected to improve fine motor skills and, consequently, writing fluency. Brain correlates and plasticity are anticipated to reflect behavioral outcomes, particularly in auditory and motor regions. By clarifying causal links between rhythm and reading/writing skills, this study will advance theoretical models and inform evidence-based educational and clinical practices.

   

O projeto LUMIRing tem como objetivo implementar uma plataforma de testes com fibra multinariz (MCF) na Linha Amarela do Metro de Lisboa — uma iniciativa ambiciosa e inovadora para explorar a transmissão em MCF fracamente acoplada em condições reais. Ao tirar partido das agressões mecânicas provocadas pelas operações do metro em túneis subterrâneos, o projeto oferece uma oportunidade única para investigar e enfrentar desafios reais de transmissão. Um objetivo central é conceber, implementar e validar técnicas avançadas que reduzam a degradação de desempenho e permitam integrar a transmissão de dados com funções de deteção, expandindo os limites das capacidades atuais de MCF. A principal infraestrutura da plataforma de testes inclui um cabo com 12 tubos, cada um contendo 12 fibras. O cabo contém 74 fibras WC-MCF com diâmetro de revestimento padrão (de 5 tipos diferentes, com 4 e 7 núcleos e com perfis de índice de refração em degrau e assistidos por vala) e 70 fibras monomodo convencionais de núcleo único (SSMF).